Clinical Evaluation of Autologous Platelet-Rich Fibrin in the Treatment of Multiple Adjacent Gingival Recession Defects: A 12-Month Study

Tunali M., ÖZDEMİR H. , ARABACI T., Gurbuzer B., Pikdoken M. L. , Firatli E.

INTERNATIONAL JOURNAL OF PERIODONTICS & RESTORATIVE DENTISTRY, vol.35, no.1, pp.105-114, 2015 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 35 Issue: 1
  • Publication Date: 2015
  • Doi Number: 10.11607/prd.1826
  • Page Numbers: pp.105-114


Leukocyte- and platelet-rich fibrin (L-PRF) belongs to a new generation of platelet concentrates. There are limited numbers of studies focused on the use of L-PRF in gingival recession defects. This study evaluated the safety and effectiveness of using L-PRF membranes as a substitute for free connective tissue grafts (CTGs) as a treatment method for gingival recession defects. A total of 44 Miller Class I/II gingival recessions that were bilateral, adjacent, and greater than 3 mm in size were selected. Each recession site was randomly assigned to the test group (L-PRF) or the control group (CTG). After 12 months, root coverage was 76.63% and 77.36% in the L-PRF and CTG groups, respectively. It is suggested that L-PRF membrane may be an alternative graft material for treating multiple adjacent recessions greater than 3 mm in size without a requirement for additional surgery.