IN VITRO COMPARISON OF THE EFFECTS OF DENTAL FILLING MATERIALS ON MOUSE FIBROBLASTS

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Kilic D., KESİM S., LİMAN N., SÜMER Z. , ÖZTÜRK A.

BIOTECHNOLOGY & BIOTECHNOLOGICAL EQUIPMENT, vol.26, no.4, pp.3155-3162, 2012 (Journal Indexed in SCI) identifier

  • Publication Type: Article / Article
  • Volume: 26 Issue: 4
  • Publication Date: 2012
  • Doi Number: 10.5504/bbeq.2012.0030
  • Title of Journal : BIOTECHNOLOGY & BIOTECHNOLOGICAL EQUIPMENT
  • Page Numbers: pp.3155-3162

Abstract

The choice of filling material is an important factor in the clinical success of root coverage. Therefore, the cytotoxicity of filling materials must be investigated to ensure a safe biological response. The aim of this study was to compare the response of L929 mouse fibroblasts to several glass ionomer cements (GICs), i.e. conventional GIC, resin-modified glass ionomer cement (RMGIC) and polyacid-modified resin composite (PMRC), using three different methods. 1) 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay 2) agar diffusion test, 3) scanning electron microscopy