IN VITRO COMPARISON OF THE EFFECTS OF DENTAL FILLING MATERIALS ON MOUSE FIBROBLASTS

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Kilic D., KESİM S., LİMAN N., SÜMER Z., ÖZTÜRK A.

BIOTECHNOLOGY & BIOTECHNOLOGICAL EQUIPMENT, cilt.26, sa.4, ss.3155-3162, 2012 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 26 Sayı: 4
  • Basım Tarihi: 2012
  • Doi Numarası: 10.5504/bbeq.2012.0030
  • Dergi Adı: BIOTECHNOLOGY & BIOTECHNOLOGICAL EQUIPMENT
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.3155-3162
  • Anahtar Kelimeler: fibroblast, MTT, cytotoxity, glass ionomer cement, cell morphology, GLASS-IONOMER CEMENTS, HUMAN GINGIVAL FIBROBLASTS, CORONALLY POSITIONED FLAP, INVITRO ASSESSMENT, HUMAN OSTEOBLASTS, MILLIPORE FILTER, COMPOSITE RESINS, CYTO-TOXICITY, ROOT SURFACE, CELL-LINES
  • Sivas Cumhuriyet Üniversitesi Adresli: Evet

Özet

The choice of filling material is an important factor in the clinical success of root coverage. Therefore, the cytotoxicity of filling materials must be investigated to ensure a safe biological response. The aim of this study was to compare the response of L929 mouse fibroblasts to several glass ionomer cements (GICs), i.e. conventional GIC, resin-modified glass ionomer cement (RMGIC) and polyacid-modified resin composite (PMRC), using three different methods. 1) 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay 2) agar diffusion test, 3) scanning electron microscopy