The Relationship Among the Level of Serum Amyloid A, High-Density Lipoprotein and Microalbuminuria in Patients With Familial Mediterranean Fever


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Uslu A. U. , Aydin B., Icagasioglu I. S. , Balta S., DEVECİ K. , ALKAN BAYLAN F. , ...More

JOURNAL OF CLINICAL LABORATORY ANALYSIS, vol.30, no.6, pp.1003-1008, 2016 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 30 Issue: 6
  • Publication Date: 2016
  • Doi Number: 10.1002/jcla.21971
  • Title of Journal : JOURNAL OF CLINICAL LABORATORY ANALYSIS
  • Page Numbers: pp.1003-1008

Abstract

BackgroundSerum amyloid A (SAA), which is produced in the liver, acts as an apoprotein of high-density lipoprotein (HDL) accumulation in extracellular matrix of tissues and organs. SAA elevations play a significant role in the development of amyloidosis. Microalbuminuria (MAU) is the early period of amyloidosis in patients with familial Mediterranean fever (FMF). We assessed the association between SAA as an important factor for the development of amyloidosis in patients with FMF and cytokines, HDL, and MAU.