The Relationship Among the Level of Serum Amyloid A, High-Density Lipoprotein and Microalbuminuria in Patients With Familial Mediterranean Fever

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Uslu A. U., Aydin B., Icagasioglu I. S., Balta S., DEVECİ K., ALKAN BAYLAN F., ...Daha Fazla

JOURNAL OF CLINICAL LABORATORY ANALYSIS, cilt.30, sa.6, ss.1003-1008, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 30 Sayı: 6
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1002/jcla.21971
  • Dergi Adı: JOURNAL OF CLINICAL LABORATORY ANALYSIS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1003-1008
  • Anahtar Kelimeler: familial Mediterranean fever, inflammation, serum amyloid A, high-density lipoprotein, microalbuminuria, SUBCLINICAL INFLAMMATION, COLCHICINE, DIAGNOSIS
  • Sivas Cumhuriyet Üniversitesi Adresli: Evet

Özet

BackgroundSerum amyloid A (SAA), which is produced in the liver, acts as an apoprotein of high-density lipoprotein (HDL) accumulation in extracellular matrix of tissues and organs. SAA elevations play a significant role in the development of amyloidosis. Microalbuminuria (MAU) is the early period of amyloidosis in patients with familial Mediterranean fever (FMF). We assessed the association between SAA as an important factor for the development of amyloidosis in patients with FMF and cytokines, HDL, and MAU.