Physicochemical properties, molecular docking and global reactivity descriptors of manganese carbonyl complexes with imidazole ligands


Gungor G., Dasdan D. S. , Ustun E., ŞAHİN N.

JOURNAL OF THE INDIAN CHEMICAL SOCIETY, cilt.96, ss.1163-1168, 2019 (SCI İndekslerine Giren Dergi) identifier

  • Cilt numarası: 96 Konu: 9
  • Basım Tarihi: 2019
  • Dergi Adı: JOURNAL OF THE INDIAN CHEMICAL SOCIETY
  • Sayfa Sayısı: ss.1163-1168

Özet

In this study, it was investigated that the solution behavior of two carbon monoxide releasing molecules; Mn(CO)(3)(bpy)(N-imidazole)]PF6 (1), [Mn(CO)(3)(bpy)(N-methylimidazole)]PF6 (2) which showed anticancer activity via zetasizer properties such as measuring particle size, electrophoretic mobility and zeta potential as a function of pH and determined the global reactivity descriptors and molecular docking poses via computational chemistry. The activities of molecules in the different pHs were checked by UV/Vis spectrophotometer.