Pulmonary lymphangitic sarcomatosis and a review of the literature


Gonlugur T., Sapmaz F., Katrancioglu O. , GÖNLÜGÜR U., Elagoz S.

CLINICAL & EXPERIMENTAL METASTASIS, vol.26, no.5, pp.399-402, 2009 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Review
  • Volume: 26 Issue: 5
  • Publication Date: 2009
  • Doi Number: 10.1007/s10585-008-9181-3
  • Title of Journal : CLINICAL & EXPERIMENTAL METASTASIS
  • Page Numbers: pp.399-402

Abstract

Intrapulmonary spread of a sarcoma via lymphatics is a rare cause of death in a young adult. A 31-year old man was admitted to our hospital complaining of dyspnea and malaise of 2 months' duration. A chest radiography revealed bilateral hilar enlargement, and reticulonodular infiltrations. Thoracic CT-scans demonstrated mediastinal lymphadenopathy, thickening of interlobular septa, polygonal lines, and thickening of bronchovascular bundles. The diagnosis was made by open-lung biopsy. The patient died within 3 months after diagnosis. Pulmonary lymphangitic sarcomatosis is a rare but important manifestation of an angiosarcoma. Optimal treatment of these patients is not well defined, but a trial of chemotherapy may be warranted.