Pulmonary lymphangitic sarcomatosis and a review of the literature

Gonlugur T., Sapmaz F., Katrancioglu O. , GÖNLÜGÜR U., Elagoz S.

CLINICAL & EXPERIMENTAL METASTASIS, cilt.26, sa.5, ss.399-402, 2009 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 26 Konu: 5
  • Basım Tarihi: 2009
  • Doi Numarası: 10.1007/s10585-008-9181-3
  • Sayfa Sayıları: ss.399-402


Intrapulmonary spread of a sarcoma via lymphatics is a rare cause of death in a young adult. A 31-year old man was admitted to our hospital complaining of dyspnea and malaise of 2 months' duration. A chest radiography revealed bilateral hilar enlargement, and reticulonodular infiltrations. Thoracic CT-scans demonstrated mediastinal lymphadenopathy, thickening of interlobular septa, polygonal lines, and thickening of bronchovascular bundles. The diagnosis was made by open-lung biopsy. The patient died within 3 months after diagnosis. Pulmonary lymphangitic sarcomatosis is a rare but important manifestation of an angiosarcoma. Optimal treatment of these patients is not well defined, but a trial of chemotherapy may be warranted.