Adenosine deaminase and xanthine oxidase levels in multiple sclerosis patients

GÖKÇE Ş. F., DEMİRPENÇE Ö., ÇİĞDEM B., BOLAYIR A., ERŞAN S.

ANNALS OF CLINICAL AND ANALYTICAL MEDICINE, cilt.11, ss.147-150, 2020 (ESCI) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 11
  • Basım Tarihi: 2020
  • Doi Numarası: 10.4328/acam.20136
  • Dergi Adı: ANNALS OF CLINICAL AND ANALYTICAL MEDICINE
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI)
  • Sayfa Sayıları: ss.147-150
  • Anahtar Kelimeler: Multiple Sclerosis, Adenosine Deaminase, Xanthine Oxidase, OXIDATIVE STRESS, DISEASE
  • Sivas Cumhuriyet Üniversitesi Adresli: Evet

Özet

Aim: Multiple sclerosis represents an autoimmune, chronic, inflammatory, and demyelinating disease of the central nervous system. Inflammation and oxidative stress are considered to take a significant part in its pathogenesis. Adenosine deaminase (ADA) and xanthine oxidase (XO) enzymes, which are involved in purine metabolism, are critical for regulating inflammation and oxidative stress. Therefore, this study's goal is to evaluate the levels of these two enzymes in patients with the relapsing-remitting type of multiple sclerosis (MS) in their remission period.