Akademik Veri Yönetim Sistemi
Bioprinting the Human, Soner Şahin,MD – Professor,Faculty of Medicine,Department of Neurosurgery,Nisantasi University,Istanbul,Turkey,Kenan Demir,MD – Health Sciences University,Samsun Training and Research Hospital,Samsun Eğitim ve Araştırma Hastanesi,İlkadım,Turkey., Editör, NOVA Science Publishers Inc. , New York, ss.17-36, 2022
Medical applications for three-dimensional (3D) printing are spreading briskly and are anticipated to reform healthcare. The current and potential medical applications of 3D printing technology can be organized into several broad categories, including fabricating porous scaffolds, orthoses devices for tissue engineering, regenerative medicine, anatomical models, and the creation of customized prosthetics, implants, and drug delivery systems. 3D printing technology applicability in treatment can offer many advantages, such as individualization and personalization of medical products, drugs, high structural complexity, medical devices, and cost-efficiency.
However, before 3D printing can be routinely used for the regeneration of complex tissues (e.g., muscle, bone, cartilage, vessels, craniomaxillofacial hard tissues) and complicated organs with complex 3D microarchitecture (e.g., liver, lymphoid organs), diverse restrictions such as biomaterial design parameters with tunable mechanical properties, optimal structures, degradation/bioactivity properties must be addressed. This book chapter will describe the leading polymer-based biomaterials and recent technological breakthroughs for the top 3D printing methods. 3D-printable polymer-based biomaterials, hydrogels, and bioinks will be highlighted according to their processability, printability, fundamental limitations, and properties such as degradation rate, biocompatibility, and mechanics.
Keywords: tissue engineering, bioprinting, hydrogels, 3D printed scaffolds, biomaterials, polymers, regenerative medicine, mechanical properties, additive manufacturing