Modulatory effects of neuropeptides on pentylenetetrazol-induced epileptic seizures and neuroinflammation in rats

Creative Commons License

Kilinc E., GÜNEŞ H.

REVISTA DA ASSOCIACAO MEDICA BRASILEIRA, cilt.65, sa.9, ss.1188-1192, 2019 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 65 Sayı: 9
  • Basım Tarihi: 2019
  • Doi Numarası: 10.1590/1806-9282.65.9.1188
  • Dergi Adı: REVISTA DA ASSOCIACAO MEDICA BRASILEIRA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1188-1192
  • Sivas Cumhuriyet Üniversitesi Adresli: Evet

Özet

OBJECTIVE: We aimed to explore the effects of neuropeptides ghrelin, obestatin, and vasoactive intestinal peptide (VIP) on seizures and plasma concentrations of neuroinflammation biomarkers including calcitonin gene-related peptide (CGRP), substance-P (SP), and interleukin-1 beta (IL-1 beta) in pentylenetetrazol-induced seizures in rats.