A Negative Correlation Between MEFV Mutations and Allergic Diseases

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YILDIRIM M. E., KÜÇÜK KURTULGAN H., KILIÇGÜN H., Duksal F.

JOURNAL OF PEDIATRIC RESEARCH, cilt.9, sa.2, ss.132-137, 2022 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 9 Sayı: 2
  • Basım Tarihi: 2022
  • Doi Numarası: 10.4274/jpr.galenos.2021.33407
  • Dergi Adı: JOURNAL OF PEDIATRIC RESEARCH
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.132-137
  • Anahtar Kelimeler: Allergic rhinitis, asthma, FMF, MEFV gene, mutation, FAMILIAL MEDITERRANEAN FEVER, T-CELLS, ATOPY, TH1, CHILDREN, POLARIZATION, PREVALENCE, CYTOKINES, RHINITIS, ASTHMA
  • Sivas Cumhuriyet Üniversitesi Adresli: Evet

Özet

Aim: Atopy is associated with a genetic predisposition to develop allergic diseases such as allergic rhinitis, asthma, and atopic dermatitis. In this study, we aimed to compare the prevalence of Familial Mediterranean Fever (FMF) mutations in asthma and allergic rhinitis patients with controls in the pediatric population and to analyse the positive or negative effect of MEFV mutations in the development of atopy.