Paraneoplastic hyperbilirubinemia in metastatic prostate cancer and review of the current literature

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GÖKÇEN P., GÖKÇEN K., ÇAKMAK E., GÖKÇE G.

TURKISH JOURNAL OF UROLOGY, cilt.45, sa.1, ss.70-72, 2019 (ESCI) identifier identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 45 Sayı: 1
  • Basım Tarihi: 2019
  • Doi Numarası: 10.5152/tud.2018.52059
  • Dergi Adı: TURKISH JOURNAL OF UROLOGY
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.70-72
  • Sivas Cumhuriyet Üniversitesi Adresli: Evet

Özet

Paraneoplastic syndromes are functional clinical disorders caused by the direct effect of the primary tumor or metastasis. The initial presenting symptom of the patients may be associated with paraneoplastic manifestations. Paraneoplastic cholestasis is most frequently defined in association with renal cell carcinoma (Stauffer's syndrome), but it is an extremely rare clinical entity seen in association with prostate cancer. Etiology of cholestasis was investigated in the case diagnosed as metastatic prostate cancer who applied to the gastroenterology outpatient clinic due to complaints of ascites and jaundice that established the diagnosis of paraneoplastic hyperbilirubinemia. We observed improvement of his cholestasis with hormonotherapy used for prostate cancer.