Objective. This study aimed to investigate the effects of different mechanical surface treatments of pre-sintered zirconium oxide (ZrO2) in an attempt to improve its bonding potential. Materials and methods. One hundred and twenty IPS e-max ZirCAD (Ivoclar Vivadent) pre-sintered zirconia blocks (7 mm diameter, 3 mm height) received six different surface treatments (n = 20): Group C was untreated (control); Group E was Er: YAG laser irradiated; Group N was Nd: YAG laser irradiated; Group SB was sandblasted, Group SN was sandblasted and Nd:YAG laser irradiated; and Group SE was sandblasted and Er: YAG laser irradiated. After the surface treatments, the average surface roughness (Ra, mu m) of each specimen was determined with a profilometer, then all the specimens were sintered. The surface roughness values were analysed through one-way ANOVA and Tukey's test. Changes in the morphological characteristics of ZrO2 were examined through scanning electron microscopy (SEM). Results. Sintered sandblasted, Er:YAG laser treatment, sandblasted + Er: YAG laser and sandblasted + Nd:YAG laser irradiation resulted in a rougher surface than the other treatments. Conclusion. Nd:YAG laser irradiation alone was not effective in altering the zirconia surface morphology.