Genetic variants in the microRNA machinery gene (Dicer) have a prognostic value in the management of endometrial cancer.


Oz M., KARAKUŞ S., Yildirim M. E., BAĞCI B., SARI İ., BAĞCI G., ...Daha Fazla

Journal of cancer research and therapeutics, cilt.14, sa.6, ss.1279-1284, 2018 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 14 Sayı: 6
  • Basım Tarihi: 2018
  • Doi Numarası: 10.4103/0973-1482.187291
  • Dergi Adı: Journal of cancer research and therapeutics
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED)
  • Sayfa Sayıları: ss.1279-1284
  • Anahtar Kelimeler: Dicer, endometrial cancer, microRNA, single nucleotide polymorphism, PREDICT PROGNOSIS, DOWN-REGULATION, EXPRESSION, DROSHA, RISK, ASSOCIATION, POLYMORPHISMS, COMPONENT
  • Sivas Cumhuriyet Üniversitesi Adresli: Evet

Özet

Aim: Although several associations were found between Dicer rs3742330 single nucleotide polymorphism (SNP) and development and prognosis of some epithelial cancers, relationship between the SNP rs3742330 and endometrial cancer (EC) has not yet been studied. We aimed to investigate the prognostic role of rs3742330 SNP of Dicer gene in EC patients.