The evaluation of two genetic polymorphisms of paraoxonase 1 in patients with pulmonary embolism

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Basol N., KARAKUŞ N., Savas A. Y., KARAKUŞ K., Kaya I., KARAMAN S., ...Daha Fazla

JOURNAL OF CLINICAL LABORATORY ANALYSIS, cilt.32, sa.7, 2018 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 32 Sayı: 7
  • Basım Tarihi: 2018
  • Doi Numarası: 10.1002/jcla.22455
  • Dergi Adı: JOURNAL OF CLINICAL LABORATORY ANALYSIS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sivas Cumhuriyet Üniversitesi Adresli: Hayır

Özet

Background and ObjectivePulmonary embolism (PE) is caused by some genetic factors for more than half patients. Paraoxonase 1 (PON1) has significant anti-oxidative and anti-inflammatory effects. According to our knowledge, there is no study researching the relation between PON 1 gene polymorphisms and PE in the literature. Therefore, it is aimed to research possible impacts of PON 1 Q192R and L55M polymorphisms on PE, considering anti-inflammatory and anti-oxidative effects of PON 1 in Turkish population.