Effect of Levosimendan in Patients with Severe Systolic Heart Failure and Worsening Renal Function


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ZORLU A. , YÜCEL H. , YONTAR O. C. , KARAHAN O., TANDOĞAN İ. , KATRANCIOĞLU N. , ...Daha Fazla

ARQUIVOS BRASILEIROS DE CARDIOLOGIA, cilt.98, ss.537-543, 2012 (SCI İndekslerine Giren Dergi) identifier

  • Cilt numarası: 98 Konu: 6
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1590/s0066-782x2012005000048
  • Dergi Adı: ARQUIVOS BRASILEIROS DE CARDIOLOGIA
  • Sayfa Sayıları: ss.537-543

Özet

Background: Levosimendan, a calcium sensitizer, increases the sensitivity of the heart to calcium, thus increasing myocardial contractility without a rise in intracellular calcium. It was recently shown that levosimendan is beneficial in improving renal function. However, it remains to be established that the beneficial effect is differentially related to renal status during index event.