Study for the Diagnostic Screening of Paroxysmal Nocturnal Hemoglobinuria in Older Patients with Unexplained Anemia and/or Cytopenia

Ozdemir Z. N. , İLHAN O., Ozet G., Falay M., Yenerel M., Tuglular T., ...Daha Fazla

CLINICAL LABORATORY, cilt.66, sa.9, ss.1709-1715, 2020 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 66 Konu: 9
  • Basım Tarihi: 2020
  • Doi Numarası: 10.7754/clin.lab.2020.191218
  • Sayfa Sayıları: ss.1709-1715


Background: Paroxysmal nocturnal hemoglobinuria (PNH) is a rare acquired hematopoietic stem cell disease that may lead to weakness and death of patients, if unrecognized and untreated. Although consensus guidelines were reviewed recently for the diagnostic screening of PNH with multi-parameter flow cytometry (FCM), until now, no study has investigated the efficiency of such clinical indications in older patients.