Target peptide recognition by S100P protein and role of central linker region and dimer interface


Tutar Y.

PROTEIN AND PEPTIDE LETTERS, cilt.13, ss.307-311, 2006 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 13 Konu: 3
  • Basım Tarihi: 2006
  • Doi Numarası: 10.2174/092986606775338380
  • Dergi Adı: PROTEIN AND PEPTIDE LETTERS
  • Sayfa Sayıları: ss.307-311

Özet

Interaction between S100P and its target protein is an essential step in several cellular functions. The amphiphatic mellitin peptide binds tightly to S100P protein in the presence of calcium cation. Since little is known about the recognition sequence, mellitin interaction form a model for S100P. Interaction between mellitin and protein examined to identify key regions required for the protein-protein interaction.