Soluble guanylyl cyclase activators increase the expression of tolerance to morphine analgesic effect

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Durmus N., Bagcivan İ., Ozdemir E., Altun A., Gursoy S.

BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY, cilt.115, sa.6, ss.334-339, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 115 Sayı: 6
  • Basım Tarihi: 2014
  • Doi Numarası: 10.4149/bll_2014_066
  • Dergi Adı: BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.334-339
  • Anahtar Kelimeler: analgesia, morphine tolerance, soluble guanylyl cyclase, NITRIC-OXIDE SYNTHASE, OPIOID TOLERANCE, ANTINOCICEPTIVE TOLERANCE, PHYSICAL-DEPENDENCE, SPINAL-CORD, RATS, PAIN, MICE, PERSPECTIVES, INHIBITION
  • Sivas Cumhuriyet Üniversitesi Adresli: Evet

Özet

Objectives: It is aimed to investigate the effects of guanylyl cyclase activation and inhibition on acute morphine antinociception and the development of tolerance to its effect.