Inflammatory protein levels in asthmatic bronchitis: A study in the Duhok population, Iraq

Creative Commons License

Al-Habib O. A., Issa H. Y., Daştan T., Durna Daştan S., Ramadhan A. A., Selamoglu Z.

Prostaglandins and Other Lipid Mediators, cilt.176, 2025 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 176
  • Basım Tarihi: 2025
  • Doi Numarası: 10.1016/j.prostaglandins.2024.106942
  • Dergi Adı: Prostaglandins and Other Lipid Mediators
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, Chemical Abstracts Core, MEDLINE, Veterinary Science Database
  • Anahtar Kelimeler: Asthmatic bronchitis, ELISA, IGF-1, IL-6 and IL-10, TNF-α
  • Sivas Cumhuriyet Üniversitesi Adresli: Evet

Özet

Objectives: This study aims to determine the levels of TNF-α, IGF-1, IL-6, and IL-10 protein in blood samples and their potential link to bronchitis-asthma diseases in the Iraq Duhok population, highlighting the prevalence of these long-term inflammatory diseases. Methods: Sixty blood samples were used and separated into patients (n = 43) and control (n = 17) groups. Serum samples were separated for each individual. Elisa method was used in terms of 4 different proteins investigated in blood samples with the manufacturer's instruction brand kits. Results: This study evaluated TNF-α, IGF-1, IL-6, and IL-10 protein levels in blood samples from asthmatic bronchitis patients in Duhok. Although these levels were elevated compared to controls, the differences were not statistically significant. Conclusion: The differences thought to be related to the bronchitis-asthma diseases could not be demonstrated between the patient and control groups in Iraq Duhok population. Future research should explore larger sample sizes and stratified patient groups to identify potential biomarkers.