Serum lipids and Lp-PLA2 activity in multiple sclerosis

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Dogan H. O. , Yilmaz F. M. , Uysal S., Mungan S., Ak F.

Turkish Journal of Biochemistry-Turk Biyokimya Dergisi, vol.39, no.4, pp.472-475, 2014 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 39 Issue: 4
  • Publication Date: 2014
  • Doi Number: 10.5505/tjb.2014.27147
  • Title of Journal : Turkish Journal of Biochemistry-Turk Biyokimya Dergisi
  • Page Numbers: pp.472-475


Objective: Multiple sclerosis (MS) is an inflammatory demyelinating disease arising from unknown origin. Dyslipidemia, T-lymphocyte mediated inflammation, lipoprotein associated oxidative activity and lipoprotein associated phospholipase A2 (Lp-PLA2) activity include the pathogenesis of MS. In the current study, we evaluated the effect of Lp-PLA2 activity and serum lipids in MS patients with different clinical stages to understand the effect these parameters on MS progression.