Effect of hypothyroidism on the purinergic responses of corpus cavernosal smooth muscle in rabbits

Yildirim M. K., Bagcivan İ., Sarac B., Kilicarslan H., Yildirim Ş., Kaya T.

INTERNATIONAL UROLOGY AND NEPHROLOGY, cilt.40, sa.3, ss.691-699, 2008 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 40 Sayı: 3
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1007/s11255-008-9332-0
  • Dergi Adı: INTERNATIONAL UROLOGY AND NEPHROLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.691-699
  • Anahtar Kelimeler: impotence, hypothyroidism, corpus cavernosum, ENDOTHELIUM-DEPENDENT RELAXATION, NITRIC-OXIDE, POTENT RELAXANT, ADENOSINE, RECEPTORS, P2Y, PURINOCEPTORS, PHYSIOLOGY, ERECTION
  • Sivas Cumhuriyet Üniversitesi Adresli: Evet

Özet

Aims Several studies have reported evidence of hormonal abnormalities in 25-35% of impotent men. Hypothyroidism has been reported to occur in 6% of impotent men. In the present study, we examined purinergic relaxation responses in hypothyroidism in an experimental rabbit model and compared them with controls to evaluate the possible involvement of the purinergic pathway.