Investigation of the relaxant effects of pancuronium, rocuronium, vecuronium and mivacurium on rat thoracic aorta


GÜRSOY S. , BAĞÇİVAN İ. , DURMUŞ N., KAYGUSUZ K. , ÖZDEMİR KOL İ. , YILDIRIM Ş. , ...More

EUROPEAN JOURNAL OF ANAESTHESIOLOGY, vol.26, no.2, pp.155-159, 2009 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 26 Issue: 2
  • Publication Date: 2009
  • Doi Number: 10.1097/eja.0b013e32831a461f
  • Title of Journal : EUROPEAN JOURNAL OF ANAESTHESIOLOGY
  • Page Numbers: pp.155-159

Abstract

Background and objective Pancuronium, vecuronium, mivacurium and rocuronium are nondepolarizing neuromuscular blocking agents, which are competitive antagonists against acetylcholine at nicotinic receptors, and considered to have no direct actions on vascular smooth muscle. We aimed to investigate the relaxant effects and possible underlying mechanisms of these agents on isolated rat thoracic aorta.