Examining the Early Period Effect of Nilotinib on Hearing: An Experimental Study.

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Bora A., Durmuş K., Terzi H., Altuntaş E. E.

The journal of international advanced otology, cilt.16, ss.77-86, 2020 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 16
  • Basım Tarihi: 2020
  • Doi Numarası: 10.5152/iao.2019.5908
  • Dergi Adı: The journal of international advanced otology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, EMBASE, MEDLINE, Directory of Open Access Journals
  • Sayfa Sayıları: ss.77-86
  • Anahtar Kelimeler: Nilotinib, ototoxicity, rat, auditory brain stem response, CHRONIC MYELOID-LEUKEMIA, DIAGNOSED CHRONIC PHASE, FOLLOW-UP, IMATINIB-RESISTANT, OCCLUSIVE DISEASE, OTOTOXICITY, INHIBITOR, EVENTS, RISK
  • Sivas Cumhuriyet Üniversitesi Adresli: Evet

Özet

OBJECTIVES: Nilotinib has very few side effects, including neutropenia, thrombocytopenia, cardiotoxicity, high pancreatic lipase, ischemia, and vascular occlusion. We aimed to investigate whether short-term administration of nilotinib had ototoxic effects in rats.