Synthesis and in vitro antioxidant evaluation of new bis(-aminoalkyl)phosphinic acid derivatives


SARAÇ K., Orek C., ÇETİN A., Dastan T. , Koparir P., DURNA DAŞTAN S. , ...More

PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS, vol.191, no.9, pp.1284-1289, 2016 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 191 Issue: 9
  • Publication Date: 2016
  • Doi Number: 10.1080/10426507.2016.1192620
  • Title of Journal : PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS
  • Page Numbers: pp.1284-1289

Abstract

Diamines were added to arylaldehydes in ethanol, which resulted in corresponding diimines. Novel bis-1-aminophosphinic acid compounds were synthesized through the interaction of diimines and hypophosphorous acid. The new compounds were characterized by elemental analyses, FT-IR and H-1, C-13 and P-31 NMR techniques. The in vitro antioxidant activity of the newly synthesized compounds were measured and found to exhibit significantly higher antioxidant activity than the standard.