Development and validation of an HPLC method for determination of carbamazepine in human plasma and applications to a therapeutic drug monitoring study


Dural E. , Cetin S., Bolayır A. , Çiğdem B.

ISTANBUL JOURNAL OF PHARMACY, vol.50, pp.6-15, 2020 (Journal Indexed in ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 50
  • Publication Date: 2020
  • Doi Number: 10.26650/istanbuljpharm.2019.0054
  • Title of Journal : ISTANBUL JOURNAL OF PHARMACY
  • Page Numbers: pp.6-15

Abstract

Background and Aims: Carbamazepine (CBZ) is an antiepileptic drug, which is prescribed as a first-line drug for the treatment of partial and generalized tonic-clonic epileptic seizures. The aim of this study was to develop and validate a simple, fast and reliable HPLC method for the determination of carbamazepine in human plasma.