Development and validation of an HPLC method for determination of carbamazepine in human plasma and applications to a therapeutic drug monitoring study


DURAL E. , Cetin S., BOLAYIR A. , ÇİĞDEM B.

ISTANBUL JOURNAL OF PHARMACY, cilt.50, ss.6-15, 2020 (ESCI İndekslerine Giren Dergi) identifier

Özet

Background and Aims: Carbamazepine (CBZ) is an antiepileptic drug, which is prescribed as a first-line drug for the treatment of partial and generalized tonic-clonic epileptic seizures. The aim of this study was to develop and validate a simple, fast and reliable HPLC method for the determination of carbamazepine in human plasma.