Development and validation of an HPLC method for determination of carbamazepine in human plasma and applications to a therapeutic drug monitoring study
ISTANBUL JOURNAL OF PHARMACY, cilt.50, ss.6-15, 2020 (ESCI, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 50
- Basım Tarihi: 2020
- Doi Numarası: 10.26650/istanbuljpharm.2019.0054
- Dergi Adı: ISTANBUL JOURNAL OF PHARMACY
- Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.6-15
- Sivas Cumhuriyet Üniversitesi Adresli: Evet
Özet
Background and Aims: Carbamazepine (CBZ) is an antiepileptic drug, which is prescribed as a first-line drug for the treatment of partial and generalized tonic-clonic epileptic seizures. The aim of this study was to develop and validate a simple, fast and reliable HPLC method for the determination of carbamazepine in human plasma.