Effects of Plant Essential Oils on Vitamin C, Malondialdehyde and Some Biochemical Parameters of Rats

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Goze I., Ersan S. , Aydın H. , Ercan N. , Donmez E.

Revista Brasileira de Ciencia Avicola, cilt.21, 2019 (SCI İndekslerine Giren Dergi) identifier identifier


The aim of this study was to determine the LD30 values of the essential oils of Origanum minutiflorum He Schwarz-PH Davis (OM) and Juniperus excelca by Bieb.subsp. Excel (JE) in vivo investigation on the effects of malondialdehyde (MDA), vitamin C and some biochemical parameters. In this, study the essential oils of OM and JE plants were used. LD50 values of the essential oils were determined by using rats. OM (n=10), JE (n=10), carvacrol (n=10) which dissolve in olive oil were used as experimental group and as control group saline (SF) (n=8) and solvent Olive oil (n=10) were used and applied intraperitoneal on rats for 12 days in LD30 dosages. In the end of 12 days, Vit-C, malondialdehyde (MDA) and routine biochemical analyses were studied on their heart bloods. The difference in the levels of MDA and Vit-C was found significant among the groups (p<0.005). When the biochemical parameters of the groups were compared, all differences in all test were found significant (p<0.005) except for creatinine (p>0.005). When the values are put to paired comparison, the differences between groups were found statistically significant (p<0.005).OM and JE has led to significant changes in all lipid peroxidation and enzyme levels.