Can SCUBE1 be used to predict the early diagnosis, lesion volume and prognosis of acute ischemic stroke?

BOLAYIR, ASLI; GÖKÇE, ŞEYDA; ÇİĞDEM, BURHANETTİN; Bolayir, VEYSEL; Gulunay, Aydin; ÇELİK, VEYSEL; KAPANCIK, SERKAN; Yildiz, ÖZLEM

doi:10.1515/tjb-2018-0040

Can SCUBE1 be used to predict the early diagnosis, lesion volume and prognosis of acute ischemic stroke?

BOLAYIR A., GÖKÇE Ş. F., ÇİĞDEM B., Bolayir H. A., Gulunay A., ÇELİK V. K., ...Daha Fazla

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, cilt.44, sa.1, ss.16-24, 2019 (SCI-Expanded, Scopus, TRDizin)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 44 Sayı: 1
Basım Tarihi: 2019
Doi Numarası: 10.1515/tjb-2018-0040
Dergi Adı: TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
Sayfa Sayıları: ss.16-24
Sivas Cumhuriyet Üniversitesi Adresli: Evet

Özet

Objective: SCUBE1 [signal peptide-CUB (complement C1r/C1 s)-EGF (epidermal growth factor)-like domain-containing protein 1] is a novel biochemical marker. SCUBE1 is thought to play roles both in platelet activation and inflammation, which are important stages for the development of acute ischemic stroke (AIS). The purpose of our study was to determine the diagnostic and prognostic values and temporal change of plasma SCUBE1 levels in AIS patients.