Novel mixed-ligand coordination frameworks, occurring concomitantly namely [Cu(Im)(3)(H(2)Cit)] (1) and [Cu(Im)(2)(HCit)]center dot HIm (2) (with Im = imidazole and H(4)Cit = citric acid) were obtained as a result of the one-pot reaction between imidazole, citric acid and copper chloride. The complexes were structurally characterized by elemental analysis, FTIR spectroscopy and X-ray diffraction. The two structures were found to be connected through 3D hydrogen-bonding networks examined by means of the Hirshfeld surface analysis which highlighted the presence of O-H center dot center dot center dot O, N-H center dot center dot center dot O and C-H center dot center dot center dot O H-bonds together with the pi center dot center dot center dot lp interactions. A topological analysis of the underlying nets corresponding to the two hydrogen-bonded frameworks was carried out. Moreover, quantum chemical calculations were performed using the HF method with 6-31G(d) and LANL2DZ levels in the gas phase, and therefore the optimized structures, the IR, H-1 NMR, C-13 NMR spectra and the electronic structure descriptors were examined in detail. Furthermore, the magnetic properties of (1) and (2) were also investigated. The complexes showed remarkable antimicrobial and antifungal inhibition activities. (C) 2018 Elsevier B.V. All rights reserved.