Determination of BPA in fruit juices using a synthesized magnetic sorbent by high-performance liquid chromatography with diode-array detection: an AMRI and MoGAPI-based method evaluation
Microchemical Journal, cilt.229, 2026 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 229
- Basım Tarihi: 2026
- Doi Numarası: 10.1016/j.microc.2026.119518
- Dergi Adı: Microchemical Journal
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, Chemical Abstracts Core, Chimica, Index Islamicus, Academic Search Ultimate (EBSCO), Engineering Source (EBSCO)
- Anahtar Kelimeler: AMRI, BPA, Endocrine disruptor, Fruit juice, Magnetic solid-phase extraction, MoGAPI
- Sivas Cumhuriyet Üniversitesi Adresli: Evet
Özet
Bisphenol A (BPA) is a widely encountered endocrine-disrupting compound that can migrate from food-contact materials into beverages, raising persistent concerns even at ultra-trace levels. Accurate determination of BPA in complex food matrices is often hindered by co-extracted interferences and the limitations of conventional sample preparation methods, particularly in terms of solvent consumption and operational efficiency. Here, a magnetic solid-phase extraction (MSPE) strategy based on a Fe3O4@SiO₂-PAN sorbent was developed for the time-efficient and selective enrichment of BPA from fruit juice samples. The integration of a magnetically responsive core with a PAN(1-(2-pyridylazo)-2-naphthol)functionalized surface enables efficient analyte capture and desorption, eliminating centrifugation or filtration steps and thereby simplifying the analytical workflow while reducing solvent usage. Under optimized conditions, the method exhibited good analytical performance, with a linear range of 10.0–600.0 ng mL−1 (r ≥ 0.9957), a limit of detection of 2.86 ng mL−1, and satisfactory precision (RSD < 7%). The sorbent showed excellent reusability, maintaining recoveries above 88% after 10 extraction cycles. The overall method performance was additionally evaluated using the analytical method reliability index (AMRI) and modified green analytical procedure index (MoGAPI), confirming a balanced combination of analytical reliability, operational practicality and green performance. The method was successfully applied to real fruit juice samples, demonstrating suitability for complex matrices.