Alternate Method for the Synthesis of Six-Membered Carbocycles with Five Stereocenters: 1,2,3,4,6-Pentasubstituted-4-hydroxy-cyclohexanes


Gezegen H. , Ceylan M.

SYNTHETIC COMMUNICATIONS, cilt.45, ss.2344-2349, 2015 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 45
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1080/00397911.2015.1080845
  • Dergi Adı: SYNTHETIC COMMUNICATIONS
  • Sayfa Sayıları: ss.2344-2349

Özet

A series of novel 1,2,3,4,6-pentasubstituted-4-hydroxy-cyclohexanes (3a-u) were synthesized from the reaction of aromatic ketones with aromatic aldehydes under mild reaction conditions in good yields. The stereochemistry of the synthesized compounds was established using 1D and 2D-NMR spectra.