NIR-responsive Fe3O4@PPy nanocomposite for efficient potential use in photothermal therapy

Getiren B., Ciplak Z., Gokalp C., Yildiz N.

JOURNAL OF APPLIED POLYMER SCIENCE, cilt.137, sa.44, 2020 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 137 Sayı: 44
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1002/app.49343
  • Dergi Adı: JOURNAL OF APPLIED POLYMER SCIENCE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, PASCAL, Aerospace Database, Applied Science & Technology Source, Biotechnology Research Abstracts, Chimica, Communication Abstracts, Compendex, INSPEC, Metadex, Civil Engineering Abstracts
  • Anahtar Kelimeler: conducting polymers, nanostructured polymers, optical properties, POLYPYRROLE NANOPARTICLES, IRON-OXIDE, FACILE SYNTHESIS, CANCER-THERAPY, PERFORMANCE, HYPERTHERMIA, NANOSPHERES, AGENTS
  • Sivas Cumhuriyet Üniversitesi Adresli: Evet

Özet

In this work, superparamagnetic Fe3O4@PPy nanocomposite with core-shell structure having strong near-infrared (NIR) absorption is synthesized via a facile two-step modified procedure. The prepared nanocomposite samples are characterized by UV-vis, FTIR, SEM, TEM, VSM, and XRD. The effects of laser power density (1.5-2.5 W cm(-2)) and aqueous concentration (0.01-0.2 mg ml(-1)) of the nanocomposite on the photothermal performance are investigated in the NIR region (808 nm). At 0.1 mg ml(-1) concentration, the temperature reaches up to 50.1 degrees C, 64.1 degrees C, and 78.4 degrees C within 10 min, under 1.5 W cm(-2), 2.0 W cm(-2), and 2.5 W cm(-2) NIR laser power density values, respectively. Photothermal conservation efficiency is calculated as 43.9% and the nanocomposite exhibits excellent photothermal stability. In summary, the core-shell Fe3O4@PPy nanocomposite is a promising candidate for photothermal therapy and simultaneous magnetic field-guided treatments.