Outcome of Desensitization Therapy in Immunologically High-Risk Kidney Transplantation: Single-Center Experience


Sinangil A., Ucar Z. A. , Koc Y. , Barlas S., Abouzahir S., Ecder S. T. , ...Daha Fazla

TRANSPLANTATION PROCEEDINGS, cilt.51, sa.7, ss.2268-2273, 2019 (SCI İndekslerine Giren Dergi) identifier identifier identifier

Özet

Aim. Sensitization to HLA antigens creates an immunologic barrier, linked to an increased risk of antibody-mediated rejection and poorer graft survival, that remains a persistent and often impenetrable deterrent to transplantation. Desensitization can improve transplantation rates in broadly sensitized kidney transplant recipients. We aimed to compare the clinical outcomes of immunologic high-risk kidney recipients who had desensitization treatment with the outcomes of those who did not.