Outcome of Desensitization Therapy in Immunologically High-Risk Kidney Transplantation: Single-Center Experience

Sinangil, Ayse; Ucar, Zuhal; Koc, YENER; Barlas, Soykan; Abouzahir, Sana; Ecder, Suleyman; Akin, Emin

doi:10.1016/j.transproceed.2019.04.068

Outcome of Desensitization Therapy in Immunologically High-Risk Kidney Transplantation: Single-Center Experience

Sinangil A., Ucar Z. A., Koc Y., Barlas S., Abouzahir S., Ecder S. T., ...Daha Fazla

TRANSPLANTATION PROCEEDINGS, cilt.51, sa.7, ss.2268-2273, 2019 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 51 Sayı: 7
Basım Tarihi: 2019
Doi Numarası: 10.1016/j.transproceed.2019.04.068
Dergi Adı: TRANSPLANTATION PROCEEDINGS
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.2268-2273
Sivas Cumhuriyet Üniversitesi Adresli: Hayır

Özet

Aim. Sensitization to HLA antigens creates an immunologic barrier, linked to an increased risk of antibody-mediated rejection and poorer graft survival, that remains a persistent and often impenetrable deterrent to transplantation. Desensitization can improve transplantation rates in broadly sensitized kidney transplant recipients. We aimed to compare the clinical outcomes of immunologic high-risk kidney recipients who had desensitization treatment with the outcomes of those who did not.