Outcome of Desensitization Therapy in Immunologically High-Risk Kidney Transplantation: Single-Center Experience


Sinangil A., Ucar Z. A. , Koc Y. , Barlas S., Abouzahir S., Ecder S. T. , ...More

TRANSPLANTATION PROCEEDINGS, vol.51, no.7, pp.2268-2273, 2019 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 51 Issue: 7
  • Publication Date: 2019
  • Doi Number: 10.1016/j.transproceed.2019.04.068
  • Title of Journal : TRANSPLANTATION PROCEEDINGS
  • Page Numbers: pp.2268-2273

Abstract

Aim. Sensitization to HLA antigens creates an immunologic barrier, linked to an increased risk of antibody-mediated rejection and poorer graft survival, that remains a persistent and often impenetrable deterrent to transplantation. Desensitization can improve transplantation rates in broadly sensitized kidney transplant recipients. We aimed to compare the clinical outcomes of immunologic high-risk kidney recipients who had desensitization treatment with the outcomes of those who did not.