Effects of NO/L-Arginine Pathway on Gallbladder Contractility in Bile Duct Ligated Guinea Pigs

Soylu S., AYDIN C., BAĞÇİVAN İ., YILDIRIM Ş., Koyuncu A., Topcu O., ...Daha Fazla

JOURNAL OF SURGICAL RESEARCH, cilt.155, sa.1, ss.70-76, 2009 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 155 Sayı: 1
  • Basım Tarihi: 2009
  • Doi Numarası: 10.1016/j.jss.2008.08.002
  • Dergi Adı: JOURNAL OF SURGICAL RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.70-76
  • Sivas Cumhuriyet Üniversitesi Adresli: Evet

Özet

Background. Common bile duct ligation (CBDL) produces gallbladder distension and acute inflammation similar to that seen in human acute acalculous cholecystitis. CBDL in the guinea pig affects smooth muscle contractility. The aim of this study was to determine whether the nitric oxide-L-arginine pathway plays a role in the inflammatory process and abnormal gallbladder contractility that occur after CBDL.