Effects of NO/L-Arginine Pathway on Gallbladder Contractility in Bile Duct Ligated Guinea Pigs

Soylu, Sinan; AYDIN, CENGİZ; BAĞÇİVAN, İHSAN; YILDIRIM, ŞAHİN; Koyuncu, Ayhan; Topcu, ÖMER; ARICI, SEMA

doi:10.1016/j.jss.2008.08.002

Effects of NO/L-Arginine Pathway on Gallbladder Contractility in Bile Duct Ligated Guinea Pigs

Soylu S., AYDIN C., BAĞÇİVAN İ., YILDIRIM Ş., Koyuncu A., Topcu Ö., ...Daha Fazla

JOURNAL OF SURGICAL RESEARCH, cilt.155, sa.1, ss.70-76, 2009 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 155 Sayı: 1
Basım Tarihi: 2009
Doi Numarası: 10.1016/j.jss.2008.08.002
Dergi Adı: JOURNAL OF SURGICAL RESEARCH
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.70-76
Sivas Cumhuriyet Üniversitesi Adresli: Evet

Özet

Background. Common bile duct ligation (CBDL) produces gallbladder distension and acute inflammation similar to that seen in human acute acalculous cholecystitis. CBDL in the guinea pig affects smooth muscle contractility. The aim of this study was to determine whether the nitric oxide-L-arginine pathway plays a role in the inflammatory process and abnormal gallbladder contractility that occur after CBDL.