Autoantibodies are not associated with familial mediterranean fever


Guler E., KAPTANOĞLU E. , ŞAHİN Ö. , CANDAN F. , HAYTA E. , ELDEN H.

ACTA REUMATOLOGICA PORTUGUESA, vol.37, no.2, pp.144-148, 2012 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 37 Issue: 2
  • Publication Date: 2012
  • Title of Journal : ACTA REUMATOLOGICA PORTUGUESA
  • Page Numbers: pp.144-148

Abstract

Objective: It has been suggested that Mediterranean fever (MEFV) gene mutations are also seen in certain autoimmune diseases and are related to severity of the disease activity. As most of the clinical symptoms of these inflammatory diseases are related to autoantibody positivity, we assessed autoantibody prevalence in patients with Familial Mediterranean fever (FMF) and investigated the relationship between clinical involvement of FMF and the autoantibodies. There are a few studies on this subject with conflicting results.