Labetalol, nebivolol, and propranolol relax human radial artery used as coronary bypass graft


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KORKMAZ Ö. , SARAÇ B. , GÖKSEL S. , YILDIRIM Ş. , BERKAN Ö. , BAĞÇİVAN İ.

JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, vol.149, no.4, pp.1036-1040, 2015 (Journal Indexed in SCI) identifier

  • Publication Type: Article / Article
  • Volume: 149 Issue: 4
  • Publication Date: 2015
  • Doi Number: 10.1016/j.jtcvs.2015.01.006
  • Title of Journal : JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
  • Page Numbers: pp.1036-1040

Abstract

Objective: Beta-blockers are a heterogeneous class of agents that are used in the treatment of many cardiovascular diseases, especially hypertension and atherosclerosis, and that are commonly prescribed after cardiac surgery. In the present study, the aim is to investigate the vasorelaxant effects of some common beta-adrenoceptor blockers on the human radial artery in vitro, as well as their relaxation mechanisms.