Labetalol, nebivolol, and propranolol relax human radial artery used as coronary bypass graft


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KORKMAZ Ö. , SARAÇ B. , GÖKSEL S. , YILDIRIM Ş. , BERKAN Ö. , BAĞÇİVAN İ.

JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, cilt.149, ss.1036-1040, 2015 (SCI İndekslerine Giren Dergi) identifier

  • Cilt numarası: 149 Konu: 4
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1016/j.jtcvs.2015.01.006
  • Dergi Adı: JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
  • Sayfa Sayıları: ss.1036-1040

Özet

Objective: Beta-blockers are a heterogeneous class of agents that are used in the treatment of many cardiovascular diseases, especially hypertension and atherosclerosis, and that are commonly prescribed after cardiac surgery. In the present study, the aim is to investigate the vasorelaxant effects of some common beta-adrenoceptor blockers on the human radial artery in vitro, as well as their relaxation mechanisms.