Labetalol, nebivolol, and propranolol relax human radial artery used as coronary bypass graft

KORKMAZ, ÖZGE; SARAÇ, BÜLENT; GÖKSEL, SABAHATTİN; YILDIRIM, ŞAHİN; BERKAN, ÖCAL; BAĞÇİVAN, İHSAN

doi:10.1016/j.jtcvs.2015.01.006

Labetalol, nebivolol, and propranolol relax human radial artery used as coronary bypass graft

KORKMAZ Ö., SARAÇ B., GÖKSEL S., YILDIRIM Ş., BERKAN Ö., BAĞÇİVAN İ.

JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, cilt.149, sa.4, ss.1036-1040, 2015 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 149 Sayı: 4
Basım Tarihi: 2015
Doi Numarası: 10.1016/j.jtcvs.2015.01.006
Dergi Adı: JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.1036-1040
Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
Sivas Cumhuriyet Üniversitesi Adresli: Evet

Özet

Objective: Beta-blockers are a heterogeneous class of agents that are used in the treatment of many cardiovascular diseases, especially hypertension and atherosclerosis, and that are commonly prescribed after cardiac surgery. In the present study, the aim is to investigate the vasorelaxant effects of some common beta-adrenoceptor blockers on the human radial artery in vitro, as well as their relaxation mechanisms.