Designing Specific HSP70 Substrate Binding Domain Inhibitor for Perturbing Protein Folding Pathways to Inhibit Cancer Mechanism

Coskun K. A., KOCA İ., GÜMÜŞ M., TUTAR Y.

ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, cilt.21, sa.11, ss.1472-1480, 2021 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 21 Sayı: 11
  • Basım Tarihi: 2021
  • Doi Numarası: 10.2174/1871520620666200918103509
  • Dergi Adı: ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Biotechnology Research Abstracts, Chemical Abstracts Core, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.1472-1480
  • Sivas Cumhuriyet Üniversitesi Adresli: Evet

Özet

Background: HSP70 is a survival factor for tumor cells in transformation and in tumor progression as well as in anti-apoptotic response.