Designing Specific HSP70 Substrate Binding Domain Inhibitor for Perturbing Protein Folding Pathways to Inhibit Cancer Mechanism


Coskun K. A. , KOCA İ., GÜMÜŞ M., TUTAR Y.

ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, cilt.21, sa.11, ss.1472-1480, 2021 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 21 Konu: 11
  • Basım Tarihi: 2021
  • Doi Numarası: 10.2174/1871520620666200918103509
  • Dergi Adı: ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY
  • Sayfa Sayıları: ss.1472-1480

Özet

Background: HSP70 is a survival factor for tumor cells in transformation and in tumor progression as well as in anti-apoptotic response.