The histopathological and morphometric investigation of the effects of systemically administered humic acid on alveolar bone loss in ligature-induced periodontitis in rats

Calisir M., Akpinar A., Poyraz Ö., Goze F., Cinar Z.

JOURNAL OF PERIODONTAL RESEARCH, cilt.51, sa.4, ss.499-507, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 51 Sayı: 4
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1111/jre.12329
  • Dergi Adı: JOURNAL OF PERIODONTAL RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.499-507
  • Anahtar Kelimeler: alveolar bone loss, experimental periodontitis, humic acid, inflammatory cytokines, INFLAMED GINGIVAL TISSUE, NECROSIS-FACTOR-ALPHA, INFLAMMATORY MEDIATORS, ANTAGONISTS INHIBIT, CLINICAL-PARAMETERS, CYTOKINE PROFILES, DISEASE, SERUM, INTERLEUKIN-1-BETA, PATHOGENESIS
  • Sivas Cumhuriyet Üniversitesi Adresli: Evet

Özet

BackgroundHumic acid is a soil extract found widely around the world. This product includes some trace elements important for human's health. The purpose of this study was to evaluate the morphometric and histopathological changes associated with an experimental periodontitis model in rats in response to systemic administration of humic acid.