Survival rates in elderly colorectal cancer patients: the impact of regional development levels Tasas de supervivencia en pacientes ancianos con cáncer colorrectal: el impacto de los niveles de desarrollo regional
Cirugia y Cirujanos, cilt.94, sa.2, ss.121-130, 2026 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 94 Sayı: 2
- Basım Tarihi: 2026
- Doi Numarası: 10.24875/ciru.25000131
- Dergi Adı: Cirugia y Cirujanos
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, Directory of Open Access Journals
- Sayfa Sayıları: ss.121-130
- Anahtar Kelimeler: Colorectal cancers, Elderly, Socioeconomic factors, Survival rate
- Sivas Cumhuriyet Üniversitesi Adresli: Evet
Özet
Objective: This study aimed to evaluate 5-year survival rates and associated prognostic factors in colorectal cancer (CRC) patients aged 65 and older. Method: This retrospective cohort study included patients aged 65 and older who were diagnosed with CRC and had completed a 5-year follow-up. Data were obtained from the Cancer Registry Database of the Sivas Health Directorate and the report of the Ministry of Industry and Technology, Türkiye. Results: A total of 257 elderly patients were analyzed. The median age was 73 years, and 60.3% were male. Adenocarcinoma was the predominant histological subtype (95.7%), with 71.2% of tumors located in the colon. At diagnosis, 57.2% of patients had metastases, and 74.7% received treatment. The 1 and 5-year survival rates were 63.8% and 39.3%. Higher survival rates were observed among patients aged 65-79, females, and those residing in urban areas. Metastasis was the strongest predictor of poor survival, with only 11.6% of metastatic patients surviving beyond 5 years. Cox regression analysis identified metastasis and lack of treatment as the most significant predictors of reduced survival. Conclusions: These findings highlight the critical need for early diagnosis and improved access to treatment in elderly CRC patients, particularly those at higher risk.