Sensitive Amperometric Detection of Hydroxylamine at Electropolymerized Curcumin Film Coated Pencil Graphite Electrode

Güneş M., Şap A., KARAKAYA S., Yaman M., DİLGİN Y.

ChemistrySelect, cilt.8, sa.18, 2023 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 8 Sayı: 18
  • Basım Tarihi: 2023
  • Doi Numarası: 10.1002/slct.202204104
  • Dergi Adı: ChemistrySelect
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier
  • Anahtar Kelimeler: amperometry, electrochemistry, electropolymerization, hydroxylamine, sensors
  • Sivas Cumhuriyet Üniversitesi Adresli: Evet

Özet

In this study, a sensitive electrochemical method was developed for the determination of hydroxylamine (H−A) using a curcumin-modified pencil graphite electrode prepared with the electropolymerization of curcumin (PolyCurc-PGE). The PolyCurc-PGE showed a remarkable electrocatalytic response for H−A oxidation compared with bare PGE. Amperometric and cyclic voltammetric measurements were performed based on the electrocatalytic oxidation of H−A at PolyCurc-PGE. Some parameters, such as monomer concentration, pH, and cycle number during electropolymerization, were optimized to obtain the best electrochemical response of the modified electrode towards H−A. Results show that the PolyCurc-PGE gives a linear response towards H−A oxidation in the range from 0.50 μM to 500 μM (R2=0.9984). In addition, the sensitivity and detection limit (LOD) of PolyCurc-PGE were found to be 5432 μA mM−1 cm2 and 0.15 μM H−A, respectively. The developed amperometric method was successfully applied to determine H−A in pharmaceutical and water samples, and acceptable results were obtained with high accuracy and precision.