MicroRNA-221/222 expression in atherosclerotic coronary artery plaque versus internal mammarian artery and in peripheral blood samples

Bildirici A. E., ARSLAN S., Sahin N., BERKAN Ö., BETON O., YILMAZ M. B.

Biomarkers, vol.23, no.7, pp.670-675, 2018 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 23 Issue: 7
  • Publication Date: 2018
  • Doi Number: 10.1080/1354750x.2018.1474260
  • Journal Name: Biomarkers
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.670-675
  • Keywords: Atherosclerosis, coronary artery disease, atherosclerotic plaque, miR-221/222, gene expression, CELL, MIR-221/222, REQUIRES, ISOFORM, PI3K
  • Sivas Cumhuriyet University Affiliated: Yes

Abstract

Background: Atherosclerosis is a disease of the arterial wall with predilection to some sites on others. MicroRNAs (miRNAs) are a class of the non-coding RNAs regulating the target gene expression at post-transcriptional level. Different miRNAs were found at distinct stages of plaque development and expression of miRNAs' might play an important role in the local behaviour of atherosclerotic plaques.