Soluble Endoglin Level Increase Occurs Prior to Development of Subclinical Structural Vascular Alterations in Diabetic Adolescents

Creative Commons License

Emeksiz H. C., Bideci A., Damar C., Derinkuyu B., Celik N., Doger E., ...Daha Fazla

JOURNAL OF CLINICAL RESEARCH IN PEDIATRIC ENDOCRINOLOGY, cilt.8, sa.3, ss.313-320, 2016 (SCI-Expanded)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 8 Sayı: 3
  • Basım Tarihi: 2016
  • Doi Numarası: 10.4274/jcrpe.2906
  • Dergi Adı: JOURNAL OF CLINICAL RESEARCH IN PEDIATRIC ENDOCRINOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.313-320
  • Anahtar Kelimeler: Type 1 diabetes mellitus, subclinical atherosclerosis, soluble endoglin, adolescents, FLOW-MEDIATED DILATION, TGF-BETA RECEPTOR, NITRIC-OXIDE, ASYMMETRIC DIMETHYLARGININE, ENDOTHELIAL DYSFUNCTION, CHILDREN, ATHEROSCLEROSIS, EXPRESSION, MELLITUS, CELLS
  • Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
  • Sivas Cumhuriyet Üniversitesi Adresli: Hayır

Özet

Objective: Soluble endoglin (S-endoglin) has been implicated as a potential marker of endothelial dysfunction (ED) and was reported to be elevated in diabetic adults, correlating with the severity of diabetic vasculopathy. However, circulating S-endoglin and its association with other markers of ED have not been formerly analyzed in the first decade of diabetes onset in adolescents with type 1 diabetes mellitus (T1DM).