Soluble Endoglin Level Increase Occurs Prior to Development of Subclinical Structural Vascular Alterations in Diabetic Adolescents

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Emeksiz H. C., Bideci A., Damar C., Derinkuyu B., Celik N., Doger E., ...Daha Fazla

JOURNAL OF CLINICAL RESEARCH IN PEDIATRIC ENDOCRINOLOGY, cilt.8, sa.3, ss.313-320, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 8 Sayı: 3
  • Basım Tarihi: 2016
  • Doi Numarası: 10.4274/jcrpe.2906
  • Dergi Adı: JOURNAL OF CLINICAL RESEARCH IN PEDIATRIC ENDOCRINOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.313-320
  • Anahtar Kelimeler: Type 1 diabetes mellitus, subclinical atherosclerosis, soluble endoglin, adolescents, FLOW-MEDIATED DILATION, TGF-BETA RECEPTOR, NITRIC-OXIDE, ASYMMETRIC DIMETHYLARGININE, ENDOTHELIAL DYSFUNCTION, CHILDREN, ATHEROSCLEROSIS, EXPRESSION, MELLITUS, CELLS
  • Sivas Cumhuriyet Üniversitesi Adresli: Hayır

Özet

Objective: Soluble endoglin (S-endoglin) has been implicated as a potential marker of endothelial dysfunction (ED) and was reported to be elevated in diabetic adults, correlating with the severity of diabetic vasculopathy. However, circulating S-endoglin and its association with other markers of ED have not been formerly analyzed in the first decade of diabetes onset in adolescents with type 1 diabetes mellitus (T1DM).