Effect of Capparis spinosa L. on cognitive impairment induced by D-galactose in mice via inhibition of oxidative stress

TURGUT N. H., KARA H., ARSLANBAŞ E., MERT D. G., TEPE B., GÜNGÖR H.

TURKISH JOURNAL OF MEDICAL SCIENCES, cilt.45, sa.5, ss.1127-1136, 2015 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 45 Sayı: 5
  • Basım Tarihi: 2015
  • Doi Numarası: 10.3906/sag-1405-95
  • Dergi Adı: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.1127-1136
  • Anahtar Kelimeler: Alzheimer disease, Capparis spinosa L., D-galactose, oxidative stress, cognitive impairment, SPECIES GROWING WILD, LIPID-PEROXIDATION, LYOPHILIZED EXTRACT, ALZHEIMERS-DISEASE, SYRINGIC ACID, SEED OILS, BRAIN, ANTIOXIDANT, MARKERS, MEMORY
  • Sivas Cumhuriyet Üniversitesi Adresli: Evet

Özet

Background/aim: To determine the phenolic acid levels and DNA damage protection potential of Capparis spinosa L. seed extract and to investigate the effect of the extract on cognitive impairment and oxidative stress in an Alzheimer disease mice model.