Objectives: The aim of this study was to compare the shear bond strength of resin cement (Rely X-U200) bonded to differently conditioned indirect composite samples. Materials and Methods: Sixty-six composite resin specimens (5 mm in diameter and 3 mm in thickness) were prepared with an indirect composite resin (Grandia) and randomly divided into six groups. Surfaces of the samples were treated with one of the following treatments; %37 phosphoric acid etching, sandblasting, 1,5 W, 2 W and 3 W erbium, chromium: Yttrium-scandium-gallium-garnet laser application. An untreated group was used as a control. In each group surface of the sample was analyzed with scanning electron microscopy. The remaining samples (n = 60) were built up with a self-adhesive resin cement (Rely X-U200) 3 mm in diameter and 2 mm height. After 24 h water storage at 37 degrees C, the prepared specimens were submitted to shear bond strength test. One-way analysis of variance was used to analyze the bond strength values of different groups. Results: Highest shear bond strength values were observed in sandblasting group however there were not statistical difference among the tested surface treatment methods. conclusion: In Shear bond strength of resin, cement was independent of the surface conditioning methods applied on tested indirect resin composite.