Light scattering from small anisotropic particles has important interests in the applications of meteorology, oceanography, communication, and nanotechnology. In this paper, the light scattering from uniaxial and biaxial small particles is investigated using the anisotropy formulation based on the finite-difference time-domain (FDTD) method, although this method has been used to analyse the isotropic particles. The obtained light scattering solutions from the isotropic small particle using the FDTD method are compared with the exact solutions obtained by Mie theory. The effects of the anisotropy and the rotation of optical axes on the light scattering are also investigated. Numerical results show that the distribution of scattered light is strongly affected by the anisotropy of the particles. Therefore, the anisotropy of the scattering particles is an important factor in several applications such as free-space optical communications.