Oxaliplatin and ototoxicity: is it really safe for hearing?

YÜCE S., ŞEKER M. M., KOÇ S., UYSAL İ. Ö., KAÇAN T., DOĞAN M., ...Daha Fazla

TURKISH JOURNAL OF MEDICAL SCIENCES, cilt.44, sa.4, ss.586-589, 2014 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 44 Sayı: 4
  • Basım Tarihi: 2014
  • Doi Numarası: 10.3906/sag-1304-76
  • Dergi Adı: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.586-589
  • Anahtar Kelimeler: Cancer, ototoxicity, oxaliplatin, III COLON-CANCER, ADJUVANT TREATMENT, STAGE-II, FLUOROURACIL, LEUCOVORIN, CISPLATIN, CAPECITABINE, EFFICACY, TRIAL
  • Sivas Cumhuriyet Üniversitesi Adresli: Evet

Özet

Background/aim: Oxaliplatin is an effective and widely used chemotherapeutic agent in the treatment of many solid tumors. The most common side effects are peripheral neuropathy, gastrointestinal toxicity, and neutropenia. There have been some case reports about ototoxicity with oxaliplatin, but no clinical trials. In this trial, we explored whether or not oxaliplatin has ototoxic effects.