Oxaliplatin and ototoxicity: is it really safe for hearing?

YÜCE S., ŞEKER M. M., KOÇ S., UYSAL İ. Ö., KAÇAN T., DOĞAN M., ...More

TURKISH JOURNAL OF MEDICAL SCIENCES, vol.44, no.4, pp.586-589, 2014 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 44 Issue: 4
  • Publication Date: 2014
  • Doi Number: 10.3906/sag-1304-76
  • Journal Name: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.586-589
  • Keywords: Cancer, ototoxicity, oxaliplatin, III COLON-CANCER, ADJUVANT TREATMENT, STAGE-II, FLUOROURACIL, LEUCOVORIN, CISPLATIN, CAPECITABINE, EFFICACY, TRIAL
  • Sivas Cumhuriyet University Affiliated: Yes

Abstract

Background/aim: Oxaliplatin is an effective and widely used chemotherapeutic agent in the treatment of many solid tumors. The most common side effects are peripheral neuropathy, gastrointestinal toxicity, and neutropenia. There have been some case reports about ototoxicity with oxaliplatin, but no clinical trials. In this trial, we explored whether or not oxaliplatin has ototoxic effects.