Significant association between MDM2 T309G polymorphism and colorectal cancer


Atabey M., TAŞ A. , Sari I., BOSTANCI M. E. , TOPÇU Ö. , SİLİĞ Y.

JOURNAL OF BUON, cilt.24, ss.1137-1142, 2019 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 24 Konu: 3
  • Basım Tarihi: 2019
  • Dergi Adı: JOURNAL OF BUON
  • Sayfa Sayıları: ss.1137-1142

Özet

Purpose: The Murine double minute 2 (MDM2) gene plays a crucial role in regulating and suppressing the function of apoptotic pathway. We investigated the relationship between MDM2 gene SNP309 (T309G) (rs2279744) polymorphism and colorectal cancer (CRC) in a Turkish population.