C-type natriuretic peptide is associated with the severity of Crimean-Congo hemorrhagic fever


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Turkdogan K. A. , Zorlu A., ENGİN A. , Guven F. M. K. , Polat M. M. , TURGUT O. O. , ...Daha Fazla

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, cilt.16, 2012 (SCI İndekslerine Giren Dergi) identifier

  • Cilt numarası: 16 Konu: 8
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1016/j.ijid.2012.04.009
  • Dergi Adı: INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Özet

Background: Crimean-Congo hemorrhagic fever (CCHF) is characterized by vascular dysfunction, indicating the involvement of endothelial cells. C-type natriuretic peptide (CNP) plays a critical role in the coordination of vascular tone and is associated with the prognosis in critically ill patients such as those with sepsis and septic shock. We investigated whether CNP is related to the severity of CCHF.