Association between multidrug resistance-1 C3435T gene polymorphism and right ventricular dysfunction in patients with chronic obstructive pulmonary disease: cross-sectional study

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Yucel O., GÜNEŞ H., Yucel H., Zorlu A.

SAO PAULO MEDICAL JOURNAL, cilt.136, sa.2, ss.140-143, 2018 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 136 Sayı: 2
  • Basım Tarihi: 2018
  • Doi Numarası: 10.1590/1516-3180.2017.0299281017
  • Dergi Adı: SAO PAULO MEDICAL JOURNAL
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.140-143
  • Sivas Cumhuriyet Üniversitesi Adresli: Evet

Özet

BACKGROUND: Right ventricular (RV) dysfunction may develop over the course of chronic obstructive pulmonary disease (COPD) and is an important predictor of morbidity and mortality Polymorphism of the multidrug resistance-1 (MDR-1) gene has been correlated with worse clinical findings among patients with COPD Our aim here was to investigate the relationship between MDR-1 C3435T gene polymorphism and RV dysfunction in COPD patients.