Association between multidrug resistance-1 C3435T gene polymorphism and right ventricular dysfunction in patients with chronic obstructive pulmonary disease: cross-sectional study


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Yucel O., GÜNEŞ H., Yucel H., Zorlu A.

SAO PAULO MEDICAL JOURNAL, cilt.136, ss.140-143, 2018 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 136 Konu: 2
  • Basım Tarihi: 2018
  • Doi Numarası: 10.1590/1516-3180.2017.0299281017
  • Dergi Adı: SAO PAULO MEDICAL JOURNAL
  • Sayfa Sayıları: ss.140-143

Özet

BACKGROUND: Right ventricular (RV) dysfunction may develop over the course of chronic obstructive pulmonary disease (COPD) and is an important predictor of morbidity and mortality Polymorphism of the multidrug resistance-1 (MDR-1) gene has been correlated with worse clinical findings among patients with COPD Our aim here was to investigate the relationship between MDR-1 C3435T gene polymorphism and RV dysfunction in COPD patients.