Antioxidant Activity Properties of Extract of Turmeric (Curcuma longa L.) Plant

SARAÇ H., TÜZÜN B.

Turkish Computational and Theoretical Chemistry, cilt.8, sa.2, ss.19-27, 2023 (Scopus) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 8 Sayı: 2
  • Basım Tarihi: 2023
  • Doi Numarası: 10.33435/tcandtc.1151666
  • Dergi Adı: Turkish Computational and Theoretical Chemistry
  • Derginin Tarandığı İndeksler: Scopus
  • Sayfa Sayıları: ss.19-27
  • Anahtar Kelimeler: Antioxidant activity, Extract, Molecular docking, Turmeric (Curcuma longa L.)
  • Sivas Cumhuriyet Üniversitesi Adresli: Evet

Özet

In this study, it was aimed to determine the chemical components in the ethanol extract of the turmeric (Curcuma longa L.) plant rhizomes sold as powder in spice-sellers and to determine its antioxidant activity properties. For this purpose, turmeric rhizomes powder was extracted by maceration method using ethanol solvent and its chemical content was determined by Gas chromatography-Mass spectrometry (GC-MS) analysis. After chemical components were determinate for the turmeric ethanol extract, the inhibitory activities of these chemicals against the Crystal structure of Human peroxiredoxin 5 (HP5) (PDB ID: 1HD2) and Bovine Xanthine Oxidase (BXO) (PDB ID: 3NRZ) downloaded from the Protein Data Bank site were compared. The highest activity of the molecule was investigated by Gaussian calculations.