Everolimus as an mTOR Inhibitor Suppresses Endometriotic Implants: an Experimental Rat Study


Kacan T., Yildiz C., Kacan S. B. , Seker M., Ozer H. , Cetin A.

GEBURTSHILFE UND FRAUENHEILKUNDE, cilt.77, ss.66-72, 2017 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 77 Konu: 1
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1055/s-0042-115566
  • Dergi Adı: GEBURTSHILFE UND FRAUENHEILKUNDE
  • Sayfa Sayıları: ss.66-72

Özet

Introduction Mammalian target of rapamycin is a pathway to block apoptosis. Recent studies showed that the activity of mammalian target of rapamycin pathway increases in endometriotic lesions. Aim of the present study was to study the effect of everolimus agent, a rapamycin analog, in an experimental endometriosis model.