Chemical Composition, Antioxidant, Antimicrobial and Antispasmodic Activities of the Essential Oil of Juniperus excelsa subsp excelsa

ATAŞ A. D., Goze I., ALİM A., ÇETİNUS Ş., DURMUŞ N., Vural N., ...Daha Fazla

JOURNAL OF ESSENTIAL OIL BEARING PLANTS, cilt.15, sa.3, ss.476-483, 2012 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 15 Sayı: 3
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1080/0972060x.2012.10644075
  • Dergi Adı: JOURNAL OF ESSENTIAL OIL BEARING PLANTS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.476-483
  • Anahtar Kelimeler: Juniperus excelsa, essential oil, antioxidant, antimicrobial, antispasmodic, MEDICINAL-PLANTS, IN-VITRO, BERRIES, LEAVES, DITERPENES
  • Sivas Cumhuriyet Üniversitesi Adresli: Evet

Özet

In this study, chemical composition, antioxidant, antimicrobial and antiospasmodic activities of the essential oil of the berries Juniperus excelsa Bieb. subsp. excelsa were evaluated in vitro. GC and GS-MS analysis of the oil resulted in the identification of 25 compounds, representing 97.2 % of the oil; alpha-pinene (46.1 %) was the main component. Essential oil showed remarkable antimicrobial activity against the test microorganisms. The sample was also subjected to a screening for its possible antioxidant activity by using 2,2-diphenyl-1- picrylhydrazyl (DPPH) and beta-carotene-linoleic acid assays. It was exhibited moderate antioxidant activity in beta-carotene-linoleic acid test system. In rat ileum, J. excelsa essential oil effect was directly investigated on spontaneous contractions. It has been found that amplitude and frequency did not change significantly at all dose concentrations. Amplitude has been inhibited % 25 and frequency has been inhibited % 20 at 1 mg/mL.